| Approved on: | 2024-12-11 |
| Brief purpose of the study: | The purpose of the study is to examine the effects of propranolol in patients with PPA, using magnetic resonance imaging (MRI) exams. We hope to determine whether MRI will help predict who will or will not respond to treatment with propranolol in primary progressive aphasia. |
| Brief summary of what participants will be asked to do: | Study procedures include MRI, buccal swab collection, and the completion of questionnaires. Participants (except healthy controls) will receive propranolol and a placebo, for approximately 9 weeks for each. |
| Basic eligibility criteria: | Age 50 and older, have a diagnosis of primary progressive aphasia and be a native English speaker. For healthy controls, no PPA diagnosis is necessary for inclusion. |
| Study contact for more information: | Please contact us at 573-884-5372 or umhsradresearch@health.missouri.edu |
| IRB Number: | 2097152 MU |
