| Approved on: | 2025-03-28 |
| Brief purpose of the study: | The research study is to investigate whether increased plasma endosomal EnNaC is positively correlated with arterial stiffening in obese or hypertensive individuals. |
| Brief summary of what participants will be asked to do: | This study involves a one-hour visiting time for a single clinic visit in the University Hospital’s Clinical & Translational Science Unit. The study visit will include a blood draw and monitoring via sensors. |
| Basic eligibility criteria: | Participants aged between 18-35 years at the time of enrollment will be recruited. Healthy volunteers are individuals without hypertension, obesity, diabetes, heart disease, renal disease and medications.
Clinical hypertension is diagnosed when systolic blood pressure is ≥130 mmHg and/or diastolic blood pressure is ≥ 80 mmHg. Obesity is diagnosed as a body mass index (BMI) > 30. Participants with hypertension on medication, or obesity with or without diabetes on medication, are eligible for recruitment. |
| Study contact for more information: | Katelyn Smith (Research Specialist 1)
(573) 884-2194
kgsmith@health.missouri.edu |
| IRB Number: | 2099320 MU |
