| Approved on: | 2025-04-09 |
| Brief purpose of the study: | This is a clinical trial. We invite you to participate in this clinical trial because you are a woman or man and 18-100 years old healthy or affected by certain endocrine, cardiometabolic, or musculoskeletal disorder(s). The purpose of this study is to validate (check the accuracy of) laboratory assays, intravenous catheter insertion, and equipment or devices and their reproducibility, which is necessary to perform high quality research on obesity and aging (type-2 diabetes, atherosclerosis, fatty liver disease, heart failure, sarcopenia, osteoporosis, etc.), nutrition, and metabolism (the process by which a substance is handled in your body) at the University of Missouri. As technology changes and we start to use new testing methods, it is necessary to compare results from old tests, equipment and devices and new tests equipment or devices and the reproducibility of these measurements to make sure we are getting accurate results. Reproducibility means performing the same test more than once to see if the same results can be achieved each time. |
| Brief summary of what participants will be asked to do: | Participation in this study may take place at the University of Missouri Clinical and Translational Science Unit and/or NextGen Center for Imaging and may be repeated within a few hours on the same day or on different days in a 6 month period. Any number or all of the tests listed below may be performed and you will be asked to initial those that you are asked to and agreed to perform. You do not have to agree to all the tests in order to participate in this study. Study tests may include: blood or urine samples, intravenous catheter placement, endothelial cell collection, muscle or adipose (fat) tissue biopsies, oral glucose tolerance test, MRI/MRS (imaging), consuming study meals, body composition assessment by dual energy x-ray absorptiometry (DEXA), vascular function testing, and a screening interview. |
| Basic eligibility criteria: | Men and women ages 18-100 years of age healthy or affected by certain endocrine or metabolic disorders |
| Study contact for more information: | Amanda Heider at ahmc4@health.missouri.edu |
| IRB Number: | 2127348 MU |
