| DEFIANCE: ClotTriever vs. Anticoagulation for DVT | Patients ages 18 and older with a deep vein thrombosis (DVT) in the leg |
| Multifunctional Porous Soft Materials for User-Friendly Skin-Interfaced Bimodal Cardiac Patches with Long-Term Biocompatibility and Antimicrobial Property | 19-35 years old |
| Motor function assessment for mild cognitive impairment, frailty, and fall risk | Ambulatory, community dwelling older adults 60 and older with and without mild cognitive impairment. |
| Cognitive strategy training to improve occupational performance via telehealth in adults with subjective cognitive decline: A feasibility study | Inclusion:
• Age (60+) (Cedres et al., 2019)
• A positive response to at least one of the following two questions ('Do you feel that you have problems with your memory or cognition?' and ‘Do you feel that your memory has become worse?')
• Self-identified activity performance goals on the Canadian Occupational Performance Measure
• Self-reported independent function in daily life
• Read, write, and speak English fluently
• Ability to provide valid informed electronic consent
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| Multifunctional Porous Soft Materials-Enabled Six-Lead Wearable Heart Monitors with Enhanced User-Friendliness and Biocompatibility and Minimized Motion Artifacts | We plan to recruit healthy volunteers aged between 19 and 35 without any restrictions based on gender, race, or ethnicity. We will exclude children, pregnant women, prisoners, and patients diagnosed with heart disease symptoms. This excludes participants with a major illness history and who have recently experienced any cardiac-related diseases. |
| Efficacy of the Improving Participation after Stroke Self-Management-Rehabilitation (IPASSR) program in sub-acute stroke | 45-85 years of age
<6 months post-stroke
able to read, write, and speak English |
| Effects of Paced Breathing and Social Evaluation on Cognitive Flexibility | 1. aged 18-40 or 60+ years old
2. No history of significant head injury or brain dysfunction
3. No current practice of meditation or other types of breathing techniques
4. Unable to comply with 12-hour caffeine, alcohol and intense exercise abstention before the study |
| Seeking young adults age 18-25 to participate in an EEG study | Individuals ages 18-25 and who have consumed at least 5 drinks containing any kind of alcohol in their lifetime may be eligible. |
| Developing and Testing Methods for Improving Contrast Enhanced MRI | Inclusion Criteria: Applies to all participants
• Age 18 and older
• Healthy subjects and patients with specific conditions or diseases including but not limited to heart disease, lung disease and brain disease. These patients will be used to test MRI methods to detect these diseases. |
| Growth hormone resistance of beta-cells in women with gestational diabetes mellitus and people with a family history of type 2 diabetes (GHRB) | Age 18-45 years old, without current pre-diabetes or diabetes, not pregnant/breastfeeding, no major medical concern, stable weight (no loss or gain in last 3 months)
Group-specific criteria:
-Gestational diabetes group- female with a full term pregnancy with one baby in the last 5 years, diagnosed with gestational diabetes or NOT diagnosed with gestational diabetes; body mass index (BMI) 18.5-44.9.
-Family history of type 2 diabetes group- male or female, a first degree relative (ex: mother, father, sibling) diagnosed with type 2 diabetes or NOT diagnosed with type 2 diabetes; BMI 30.0-44.9. |
| Teenagers and texting: A multimethod examination of social support in adolescent friends’ text messages and associations with adjustment | We are looking for youth currently in high school (9th-12th grade) or starting high school in the fall. To be eligible for the study, adolescents must participate with a close friend. In addition, participation requires owning a smartphone and using it to communicate with the participating friend. |
| Immune Response Against Influenza or COVID-19 Infection | Individuals who are:
• At least 18years old and older;
• Self-reported Influenza-like-illness (ILI) symptoms within five days of enrollment or tested Influenza or COVID-19 positive within five days of symptom onset;
• Willing to provide a nasal swab at enrollment only for eligibility for the blood sampling part of the study
• English speaking
|
| Mental Processes for Rating Pain Intensity | General inclusion criteria: (1) 18 years old or older; (2) visited a HCP for treatment of a painful musculoskeletal condition within previous year; (3) has usually felt, at least, "mild" musculoskeletal pain on most days of the last 3 months in multiple locations; and (4) has felt variable musculoskeletal pain intensity during the last 3 months.
General exclusion criteria: (1) past or current employment as a licensed healthcare provider; (2) diagnosed with a cardiac arrhythmia; (3) has a battery-powered implant in the neck, chest, abdomen, or spine (e.g., pacemaker); (4) diagnosed with a neurological condition that causes uncontrolled movement (e.g., Parkinsonism, epilepsy, etc.); (5) smokes cigarettes or vapes; (6) has abused substances during the last week; or (7) allergic to skin adhesives. |
| Characterizing Information Needs and Design Requirements to Develop a Digital Tool that Provides Evidence-based Information about Opioid User Disorder Treatment for Pregnant Information Seekers | A nurse practitioner, physician, or physician assistant with experience treating opioid use disorder OR a person who has 1) previously been pregnant and is not currently pregnant and 2) previously experienced an opioid use disorder. Past pregnancy and opioid use disorder need not have occurred at the same time. |
| Seeking adults aged 21-25 who drink alcohol for EEG study on reward learning | Individuals age 21-25 who drank alcohol at least two days in the past month may be eligible. |
| Cerebral Lactate Uptake and Transport in Obese and Non-Obese Individuals | All subjects will report being healthy adult men and women, 18-45 years of age, BMI 18-40 kg/m2, not pregnant, not breastfeeding, and non-nicotine users. Women must be premenopausal. Subjects can not exercise more than 3 days/wk. |
| Integration of Advanced Materials and Wearable Devices for Human Physiological Signal Monitoring | We plan to recruit healthy volunteers aged between 19 and 65. The participants had no medical or surgical problems history. The process without any restrictions based on gender, race, or ethnicity. |
| Associations and Interactions of Sleep, Pain, and Cognition | You may be eligible to participate if you 18+ yo, are MRI eligible (not pregnant or have any internal metal objects), and struggle with sleep and/or pain. Other inclusion/exclusion criteria may apply. |
| Cultural Identification with Middle Eastern Students Living in the Diaspora | Participants must identify as a first- or second-generation immigrant. In the context of this study, a first-generation immigrant is an individual who immigrated from their homeland to the United States, while a second-generation immigrant is the child of at least one first-generation immigration. |
| A Research Study about Children's Storytelling | Participating children must be between ages 6-and-12 years old. Families must live in Missouri. Families should predominantly use English in the home. If participating remotely, children need to be able to work from a device with a larger screen and active webcam, like a tablet or laptop, to best complete the Fairy Tale Test. Children must not have a formal diagnosis of intellectual disability or autism spectrum disorder. |
| Routine validation and reproducibility testing of laboratory assays and research techniques used for endocrine, cardiometabolic, and musculoskeletal disorder research (VALD) | Men and women ages 18-100 years of age healthy or affected by certain endocrine or metabolic disorders |
| Missouri Households and Family Research Participant Database | Subjects ages 18 and older within the State of Missouri. |
| Assessment of Dissolved Phase 129Xe as a Biomarker for Gas-Exchange and Vascular Function in Asthma
| Age 18-35 years old, or age 45 and older
Diagnosed with mild, moderate or severe asthma – or no history of lung disease (healthy controls)
Must be at their clinical baseline and be clinically stable
Capacity to give informed consent |
| Cue-topia: Neurocognitive Mechanisms of Cue Learning in Adults. | -Adults aged 18 to 65
-Reside in Boone or adjacent counties
-have normal or corrected-to-normal visual acuity, normal color vision, and no history of neurological problems |
| ACUTE EFFECTS OF INSPIRATORY MUSCLE TRAINING ON NEUROVASCULAR AND COGNITIVE RESPONSES TO SEDENTARY BEHAVIOR | All eligible participants will be healthy men and women, 18-45 years of age, non-pregnant, non-breastfeeding, and non-nicotine users. Participants will have a body mass index (BMI) ≥18 kg/m2 and ≤30 kg/m2. Premenopausal women will have a negative pregnancy test (urine) within 48 (about 4 days) of their visits and will be studied during the early follicular phase of the menstrual cycle or placebo phase of oral contraceptive use to minimize potential effects of reproductive hormone status on study results. Participants will be excluded if they are taking any medications known to affect metabolic, autonomic, and/or respiratory function (e.g. α-blockers, β-blockers, etc.), have a self-reported history of hepatic, renal, pulmonary, cardiovascular, or neurological disease, stroke or neurovascular disease, bleeding/clotting disorders, sleep apnea or other sleep disorders, diabetes, smoking, history of alcoholism or substance abuse, or hypertension (>140/90 mmHg or at PIs discretion). |
